[HLA antigens in Chagas cardiomyopathy: new evidence based on a case-control study].

Abstract

We studied the distribution of HLA, B and C antigens in 73 Chagasic subjects with and without heart disease. Both groups were matched for age, sex, birth place and history of family residence. Thirty two subjects without evidence of Chagasic infection, with and without heart disease and matched for the same variables were also studied. Compared to all other groups, a significant increase in the level of the B40 Cw3 antigen combination was found in Chagasic subjects without evidence of heart disease.

• Authors: E Llop, F Rothhammer, M Acuña, W Apt, A Arribada
• Journal: Revista medica de Chile (Rev Med Chil) Vol. 119 Issue 6 Pg. 633-6 (Jun 1991) ISSN: 0034-9887 [Print] Chile
• Vernacular Title: Antígenos HLA en cardiopatas chagásicos: nueva evidencia basada en un análisis de casos y controles.
• PMID: 1844366 (Publication Type: Comparative Study, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• HLA-B Antigens
• HLA-B40 Antigen
• HLA-C Antigens
• HLA-C*03 antigen

Topics

• Adult
• Case-Control Studies
• Chagas Cardiomyopathy (blood, epidemiology, immunology)
• Chile (epidemiology)
• HLA-B Antigens (analysis)
• HLA-B40 Antigen
• HLA-C Antigens (analysis)
• Humans
• Male