Correlation of autism with temporal tubers in tuberous sclerosis complex.

Abstract

Tuberous sclerosis complex (TSC) is an inherited genetic disorder commonly associated with neuropsychiatric complications like epilepsy, mental retardation, autism and other behavioral problems and constitutes about 1-4% of the autistic population. Mental retardation and seizures, particularly infantile spasms are significant risk factors for the development of autism. Patients of TSC with autism are more likely to have temporal tubers than those cases without autism. We describe clinical and neuroimaging features of two such cases of tuberous sclerosis with autism.

• Authors: Kavitha Kothur, Munni Ray, Prahbhjot Malhi
• Journal: Neurology India (Neurol India) 2008 Jan-Mar Vol. 56 Issue 1 Pg. 74-6 ISSN: 0028-3886 [Print] India
• PMID: 18310844 (Publication Type: Case Reports, Journal Article)

Topics

• Autistic Disorder (complications, pathology)
• Child
• Child, Preschool
• Female
• Humans
• Intellectual Disability (complications, pathology)
• Magnetic Resonance Imaging (methods)
• Male
• Temporal Lobe (pathology)
• Tuberous Sclerosis (complications, pathology)