Abstract | BACKGROUND: STUDY DESIGN: RESULTS: Causes of liver failure included hepatitis B (n=12), hepatitis C (n=1), autoimmune hepatitis (n=2), Wilson's disease (n=3), and unknown causes (n=24). The graft types were: left lobe (n=33), right lobe (n=8), and lateral segment (n=1). The mean graft volume to standard liver volume ratios were 42.2+/-9.2% in left lobe grafts and 50.5+/-3.9% in right lobe grafts (p < 0.05). Extubation was significantly delayed in grade IV encephalopathy patients (73.7 +/-18.2 hours) compared with patients with other grades (p < 0.01 to grades I and II, p < 0.05 to grade III). All other patients, except one with a subarachnoid hemorrhage, had complete neurologic recovery after transplantation. The 1- and 10-year survival rates were 77.6% and 65.5%, respectively, for grafts, and 80.0% and 68.2%, respectively, for patients. CONCLUSIONS:
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Authors | Toru Ikegami, Akinobu Taketomi, Yuji Soejima, Tomoharu Yoshizumi, Kensaku Sanefuji, Hiroto Kayashima, Mitsuo Shimada, Yoshihiko Maehara |
Journal | Journal of the American College of Surgeons
(J Am Coll Surg)
Vol. 206
Issue 3
Pg. 412-8
(Mar 2008)
ISSN: 1879-1190 [Electronic] United States |
PMID | 18308209
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Cohort Studies
- Female
- Graft Survival
- Hepatic Encephalopathy
(etiology)
- Hospitals, University
- Humans
- Infant
- Japan
- Liver Failure, Acute
(etiology, mortality, surgery)
- Liver Transplantation
- Living Donors
- Male
- Middle Aged
- Survival Rate
- Time Factors
- Treatment Outcome
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