Abstract | PURPOSE: To evaluate the influence of preoperative variables and early postoperative intraocular pressure (IOP) on the loss of corneal endothelial cells after phacoemulsification in eyes with occludable angles. SETTING: Taipei Veterans General Hospital, Taipei, Taiwan. METHODS: Sixty patients with occludable angles having phacoemulsification were prospectively enrolled. Corneal endothelial cell evaluation was conducted preoperatively and 3 months postoperatively. RESULTS: Three months postoperatively, the mean corneal endothelial cell density decreased by 14.5% +/- 25.8% (SD) (P < .001). Greater corneal endothelial cell loss was associated with shorter axial length (AL) (P = .008), steeper anterior corneal curvature (P = .03), greater nuclear opalescence (P = .04), and higher IOP measured 4 to 8 hours after surgery (P = .04) and the following morning (P = .002). Multiple linear regression analysis identified AL and the IOP measured 4 to 8 hours after surgery as the best predictors of postoperative corneal endothelial cell loss after adjusting for nuclear opalescence and phacoemulsification time (R2 = 0.40, P = .001). CONCLUSIONS:
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Authors | Yu-Chieh Ko, Catherine Jui-ling Liu, Ling-Ing Lau, Chih-Wei Wu, Joe C Chou, Wen-Ming Hsu |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 34
Issue 1
Pg. 46-51
(Jan 2008)
ISSN: 0886-3350 [Print] United States |
PMID | 18165080
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Aged
- Aged, 80 and over
- Anterior Eye Segment
(pathology)
- Cell Count
- Corneal Diseases
(etiology)
- Endothelium, Corneal
(pathology)
- Female
- Glaucoma, Angle-Closure
(complications)
- Humans
- Intraocular Pressure
- Male
- Middle Aged
- Phacoemulsification
- Postoperative Complications
- Prospective Studies
- Risk Factors
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