Pertussis and respiratory syncytial virus infections.

Abstract

During the winter 2005-2006, all infants <4 months of age admitted for bronchiolitis or acute respiratory tract infection in a tertiary care pediatric hospital in Paris were tested for respiratory syncytial virus (RSV) and pertussis with real-time polymerase-chain reaction (RT-PCR). A positive pertussis-PCR was found in 14/90 (16%) infants infected with RSV and in 5/30 negative for RSV. Similar clinical symptoms were found in all RSV-positive infants with or without pertussis co-infection. Most infants (73%) were not vaccinated against pertussis, and the other children had received one or two injections. In conclusion, pertussis-RSV co-infection is common in young infants, and pertussis-PCR should be used, whenever available.

• Authors: Cécile Cosnes-Lambe, Josette Raymond, Martin Chalumeau, Charlotte Pons-Catalano, Florence Moulin, Nathalie de Suremain, Hélène Reglier-Poupet, Pierre Lebon, Claire Poyart, Dominique Gendrel
• Journal: European journal of pediatrics (Eur J Pediatr) Vol. 167 Issue 9 Pg. 1017-9 (Sep 2008) ISSN: 1432-1076 [Electronic] Germany
• PMID: 18034357 (Publication Type: Journal Article)

Chemical References

• Pertussis Vaccine

Topics

• Female
• Hospitals, Pediatric
• Humans
• Infant
• Male
• Paris (epidemiology)
• Pertussis Vaccine (administration & dosage)
• Prevalence
• Prospective Studies
• Respiratory Syncytial Virus Infections (complications, epidemiology)
• Respiratory Syncytial Viruses (isolation & purification)
• Reverse Transcriptase Polymerase Chain Reaction
• Whooping Cough (complications, epidemiology, prevention & control)