The radiology of antibiotic-impregnated cement.

Abstract

OBJECTIVE:

The purpose of this article is to illustrate the radiologic appearances of the various forms of antibiotic-impregnated cement.

CONCLUSION:

Although the radiologic appearances of antibiotic-impregnated polymethyl methacrylate (PMMA) and regular PMMA are identical, peculiarities in the position and morphology of antibiotic-impregnated cement, as illustrated in this review, usually enable the radiologist to differentiate between the two. Its presence indicates one of two things: Either infection was present at the time the PMMA cement was inserted, or there was a high potential for the development of local sepsis, such as in cases of an open fracture. On the basis of this finding, the radiologist should carefully search for evidence of osteomyelitis.

• Authors: Eric J Heffernan, Fahad O Alkubaidan, Lawrence M White, Bassam A Masri, Peter L Munk
• Journal: AJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 189 Issue 2 Pg. 446-54 (Aug 2007) ISSN: 1546-3141 [Electronic] United States
• PMID: 17646473 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• Bone Cements
• Polymethyl Methacrylate

Topics

• Anti-Bacterial Agents (administration & dosage)
• Arthroplasty, Replacement
• Biofilms
• Bone Cements (chemistry)
• Drug Delivery Systems
• Fracture Healing (drug effects)
• Fractures, Bone (diagnostic imaging, drug therapy)
• Humans
• Osteomyelitis (diagnostic imaging, drug therapy)
• Polymethyl Methacrylate (chemistry)
• Prosthesis-Related Infections (diagnostic imaging, drug therapy)
• Radiography, Interventional
• Reoperation