Botulinum toxin injection into Riolan's muscle: somatosensory 'trick'.

Abstract

We studied the effect of injecting botulinum toxin A (BTX-A) into the pars ciliaris--also known as Riolan's muscle--of patients with eyelid apraxia (ELA). Six patients with ELA were treated with injections of BTX-A into the region of Riolan's muscle at the medial and lateral portions of the upper and lower pretarsal orbicularis oculi. Clinical benefit was seen in all 6 patients, 2 of whom had previously been treated with conventional pretarsal injections of BTX-A and had not improved. BTX-A injections into Riolan's muscle are effective as treatment for ELA. The proposed mechanism is not that of muscle relaxation but rather modulation of the somatosensory cortex, similar to that of a 'sensory trick' in patients with dystonia.

• Authors: Ken Inoue, John D Rogers
• Journal: European neurology (Eur Neurol) Vol. 58 Issue 3 Pg. 138-41 ( 2007) ISSN: 1421-9913 [Electronic] Switzerland
• PMID: 17622718 (Publication Type: Clinical Trial, Journal Article)
• Copyright: 2007 S. Karger AG, Basel

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Aged
• Apraxias (drug therapy)
• Botulinum Toxins, Type A (therapeutic use)
• Disability Evaluation
• Eyelids
• Female
• Follow-Up Studies
• Humans
• Injections, Intramuscular
• Male
• Middle Aged
• Neuromuscular Agents (therapeutic use)
• Oculomotor Muscles (innervation)
• Time Factors