Abstract | BACKGROUND: METHODS: RESULTS: Enhancement of sensorimotor recovery, as assessed by forelimb and hindlimb placing and body swing tests, was seen with Cerebrolysin treatment, especially at the 2.5 ml/kg dose. At this dose, enhanced recovery was found when Cerebrolysin treatment was begun at 24 or 48 (but not 72 hours) after stroke onset. There were no effects on body weight or infarct volume when Cerebrolysin was administered in this manner. CONCLUSIONS: These results suggest that Cerebrolysin may be a useful treatment for enhancing neurological recovery after stroke.
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Authors | JingMei Ren, Dana Sietsma, Shumei Qiu, Herbert Moessler, Seth P Finklestein |
Journal | Restorative neurology and neuroscience
(Restor Neurol Neurosci)
Vol. 25
Issue 1
Pg. 25-31
( 2007)
ISSN: 0922-6028 [Print] Netherlands |
PMID | 17473393
(Publication Type: Journal Article)
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Chemical References |
- Amino Acids
- Neuroprotective Agents
- cerebrolysin
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Topics |
- Amino Acids
(therapeutic use)
- Analysis of Variance
- Animals
- Cerebral Infarction
(drug therapy)
- Dose-Response Relationship, Drug
- Functional Laterality
(drug effects)
- Male
- Neuroprotective Agents
(therapeutic use)
- Psychomotor Performance
(drug effects)
- Rats
- Rats, Sprague-Dawley
- Recovery of Function
(drug effects)
- Stroke
(complications)
- Time Factors
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