[Effects of vitamin D on non-classical target organs and survival].

Abstract

Impaired activation of vitamin D in renal failure results in bone and mineral abnormalities, and causes renal osteodystrophy or chronic kidney disease mineral and bone disorder (CKD-MBD). Recent studies suggest that deficiency of active vitamin D is also involved in abnormalities in blood pressure, cardiac hypertrophy, atherosclerosis, glucose intolerance and immune dysfunction that are known as complications of uremia. This article reviews these extra-renal actions of vitamin D and its impact on survival of dialysis patients.

• Authors: Tetsuo Shoji, Yoshiki Nishizawa
• Journal: Clinical calcium (Clin Calcium) Vol. 17 Issue 5 Pg. 691-7 (May 2007) ISSN: 0917-5857 [Print] Japan
• PMID: 17470997 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Vitamin D

Topics

• Calcinosis (etiology)
• Endothelial Cells (physiology)
• Humans
• Immunity (physiology)
• Inflammation (physiopathology)
• Mortality
• Prognosis
• Vitamin D (physiology)