Aminocaproic-acid seal to reduce or prevent bleeding after liver biopsy.

Abstract

This study investigates the efficacy of an aminocaproic-acid seal to prevent or reduce the risk of bleeding attendant to liver biopsies. The simple technique of occluding the biopsy tract by injecting 1-2 mL of aminocaproic acid, a fibrinolysis inhibitor, while withdrawing the biopsy sheath appears to reduce substantially the risk of delayed bleeding. The technique may be most useful if large core biopsy needles must be used to provide an adequate specimen.

• Authors: Erich K Lang, Leann Myers, Douglas Slakey, Brian Rogers, Melissa Brammer, F Regenstein
• Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society (J La State Med Soc) 2007 Jan-Feb Vol. 159 Issue 1 Pg. 46-9 ISSN: 0024-6921 [Print] United States
• PMID: 17396476 (Publication Type: Journal Article)

Chemical References

• Aminocaproates
• Antifibrinolytic Agents

Topics

• Adolescent
• Adult
• Aged
• Aminocaproates (administration & dosage)
• Antifibrinolytic Agents (administration & dosage)
• Biopsy (adverse effects, instrumentation)
• Child
• Child, Preschool
• Chronic Disease
• Equipment Design
• Female
• Hemostatic Techniques
• Humans
• Liver (pathology)
• Liver Diseases (pathology)
• Male
• Middle Aged
• Postoperative Hemorrhage (etiology, prevention & control)
• Retrospective Studies