[The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients].

Abstract

Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.

• Authors: Ronit Grinbaum, Aviram Nissan, Nahum Beglaibter, Tzeela Cohen, Tamar Peretz, Herbert R Freund
• Journal: Harefuah (Harefuah) Vol. 145 Issue 11 Pg. 793-4, 863 (Nov 2006) ISSN: 0017-7768 [Print] Israel
• PMID: 17183947 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biomarkers, Tumor
• CA-19-9 Antigen

Topics

• Adult
• Biomarkers, Tumor (blood)
• CA-19-9 Antigen (blood)
• Female
• Humans
• Male
• Middle Aged
• Pancreatic Neoplasms (blood, mortality, surgery)
• Preoperative Care
• Prognosis
• Survival Analysis