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The value of pancreatic pseudocyst amylase concentration in the detection of pseudocyst communication with the pancreatic duct.

Abstract
The aims of the study were to compare the results of endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous cystopancreatography (PCP) in the detection of the communication between the pancreatic pseudocyst and the pancreatic duct, and to assess the reliability of the increased amylase concentration in the pseudocyst content as an indicator of the existence of communication between the pancreatic pseudocyst and the pancreatic duct system. Forty-three patients were included in the study. Pseudocystic fluid content was obtained by percutaneous aspiration. Twenty-four patients had pseudocyst amylase concentrations above 64 Wolgemuth units (WU), and 19 patients had less than 64 WU. The communication between pseudocyst and the pancreatic duct was determined in 22 patients by ERCP and in 13 patients by PCP, all in the group with increased pseudocyst amylase concentration. Due to high sensitivity and specificity of pseudocyst amylase concentration for the existence of pseudocyst communication with the pancreatic duct, we conclude that guided percutaneous aspiration of the pancreatic pseudocyst with the determination of amylase concentration in the fluid can replace ERCP as a method of choice for the detection of pseudocyst communication with the pancreatic duct.
AuthorsM Duvnjak, I Rotkvić, B Vucelić, P Sikirić, T Brkić, M Banić, B Troskot, V Supanc
JournalThe American journal of gastroenterology (Am J Gastroenterol) Vol. 86 Issue 5 Pg. 595-8 (May 1991) ISSN: 0002-9270 [Print] United States
PMID1709337 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Amylases
Topics
  • Adult
  • Amylases (metabolism)
  • Biopsy, Needle
  • Cholangiopancreatography, Endoscopic Retrograde
  • Clinical Enzyme Tests
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Ducts (pathology)
  • Pancreatic Fistula (diagnosis)
  • Pancreatic Pseudocyst (diagnosis, pathology)

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