Abstract | OBJECTIVE: METHODS: Six domestic pigs underwent median sternotomy. The pulmonary veins were circumferentially ablated. Electrical isolation was confirmed by pacing. Eight lesions were performed epicardially, and three lesions were performed through purse-string sutures with one of the jaws of the device introduced into the right atrium. After 30 days, magnetic resonance imaging was performed to assess atrial function, pulmonary vein anatomy, and coronary artery patency. Cholinergic stimulation and burst pacing were administered to induce atrial fibrillation. Histologic assessment of the heart was performed after the animal was killed. RESULTS: CONCLUSION: Lesions on both the right and left atria can be created successfully on the beating heart with irrigated bipolar radiofrequency. The great majority of lesions with this device were transmural. This device should not be used on valvular tissue.
|
Authors | Spencer J Melby, Sydney L Gaynor, Jordon G Lubahn, Anson M Lee, Paymon Rahgozar, Shelton D Caruthers, Todd A Williams, Richard B Schuessler, Ralph J Damiano Jr |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 132
Issue 4
Pg. 853-60
(Oct 2006)
ISSN: 1097-685X [Electronic] United States |
PMID | 17000297
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
|
Topics |
- Animals
- Catheter Ablation
(adverse effects, methods)
- Magnetic Resonance Imaging
- Myocardium
(pathology)
- Swine
- Therapeutic Irrigation
- Time Factors
|