Abstract | OBJECTIVE:
Chronic granulomatous disease is a rare clinical entity characterized by recurrent infective and inflammatory complications. Patients are usually assigned to specialist centres, but nonspecialist clinicians may be required to treat these patients in the emergency setting. This review serves as a management guide to those clinicians who are faced with patients presenting with gastrointestinal manifestations of chronic granulomatous disease. METHODS: This review is based on a literature search (Medline and NLM PubMed) with manual cross-referencing of all articles related to gastrointestinal chronic granulomatous disease. RESULTS: CONCLUSION: Early involvement of a centre with immunological expertise combined with aggressive management of complications significantly improves morbidity and mortality from this rare condition.
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Authors | A Huang, F Abbasakoor, C J Vaizey |
Journal | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
(Colorectal Dis)
Vol. 8
Issue 8
Pg. 637-44
(Oct 2006)
ISSN: 1462-8910 [Print] England |
PMID | 16970572
(Publication Type: Journal Article, Review)
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Topics |
- Bacterial Infections
(drug therapy, etiology, surgery, therapy)
- Gastroenteritis
(etiology, therapy)
- Granulomatous Disease, Chronic
(complications, diagnosis, therapy)
- Humans
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