[Use of antiglaucoma therapy to reduce acute intraocular pressure rise following neodymium: YAG laser iridotomy in angle-closure glaucoma patients].

Abstract

AIM:

To evaluate the efficacy of topical antiglaucoma therapy in reducing acute intraocular pressure (IOP) elevation after neodymium: Yag laser iridotomy.

PATIENTS AND METHODS:

Primary angle-closure glaucoma (PACG) eyes were randomized to receive premedication with latanoprost and pilocarpine, brimonidine 0.2% and pilocarpine or only with pilocarpine before Yag laser iridotomy. Postoperative IOP changes were compared with Wilcoxon signed-ranks test using the fellow eyes in each group.

RESULTS:

Postoperative pressure spikes were significantly lower in the groups of patients with local antiglaucoma therapy with pilocarpine than in the control group. Mean elevation of IOP was less in the groups of patients with local antiglaucoma therapy with pilocarpine at 2 hours postoperatively.

CONCLUSION:

Local antiglaucoma therapy may reduce the acute IOP rise following Yag laser iridotomy in PACG eyes.

• Authors: Katia Novak-Laus, Sanja Masnec-Paskvalin, Jadranka Korsić, Renata Iveković, Mia Zorić-Geber, Zdravko Mandić
• Journal: Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti (Acta Med Croatica) Vol. 60 Issue 2 Pg. 113-6 ( 2006) ISSN: 1330-0164 [Print] Croatia
• Vernacular Title: Lokalna terapija glaukoma u redukciji akutnog povisenja intraokularnog tlaka u bolesnika s glaukomom zatvorenog kuta nakon neodymium: YAG laserske iridotomije.
• PMID: 16848200 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Antihypertensive Agents
• Miotics
• Prostaglandins F, Synthetic
• Quinoxalines
• Pilocarpine
• Brimonidine Tartrate
• Latanoprost

Topics

• Aged
• Aged, 80 and over
• Antihypertensive Agents (administration & dosage)
• Brimonidine Tartrate
• Drug Therapy, Combination
• Female
• Glaucoma, Angle-Closure (drug therapy, surgery)
• Humans
• Iris (surgery)
• Laser Therapy
• Latanoprost
• Male
• Middle Aged
• Miotics (administration & dosage)
• Ocular Hypertension (prevention & control)
• Pilocarpine (administration & dosage)
• Postoperative Complications (prevention & control)
• Prostaglandins F, Synthetic (administration & dosage)
• Quinoxalines (administration & dosage)