Otago Glaucoma Surgery Outcome Study: follow-up of young patients who underwent Molteno implant surgery.

Abstract

OBJECTIVE:

To provide data on the results of patients with nonneovascular juvenile glaucoma who had Molteno implant surgery in the province of Otago, New Zealand.

DESIGN:

Prospective noncomparative case series.

PARTICIPANTS:

Fifty-five operations in 52 eyes of 45 patients with nonneovascular juvenile glaucoma who had Molteno implant surgery between the ages of 9 and 49 years from 1976 to 2003 at Dunedin Hospital and were observed for a mean of 12.2 years (range, 0.1-25).

INTERVENTION:

Insertion of a Molteno implant.

MAIN OUTCOME MEASURES:

Intraocular pressure (IOP) and visual acuity (VA).

RESULTS:

Insertion of a Molteno implant controlled IOP at < or =21 mmHg with probabilities of 0.89 (95% confidence interval [CI], 0.81-0.97) at both 1 and 2 years and 0.85 (95% CI, 0.75-0.95), 0.78 (95% CI, 0.66-0.90), and 0.71 (95% CI, 0.58-0.85) at 5, 10, and 15 years, respectively. Mean VA was 20/100 preoperatively; improved to 20/60 at 1 year; and stabilized at 20/120 at 5, 10, and 15 years postoperatively. Twenty-nine eyes had their preoperative VA maintained or improved at final follow-up, and the VAs of 17 eyes deteriorated but were at least light perception at final follow-up.

CONCLUSION:

The use of Molteno implants in cases of nonneovascular juvenile glaucoma controlled IOP with a probability of 0.71 15 years postoperatively, whereas 53% maintained or improved their vision from their preoperative VA at final follow-up.

• Authors: John J Ah-Chan, Anthony C B Molteno, Tui H Bevin, Peter Herbison
• Journal: Ophthalmology (Ophthalmology) Vol. 112 Issue 12 Pg. 2137-42 (Dec 2005) ISSN: 1549-4713 [Electronic] United States
• PMID: 16325709 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antihypertensive Agents

Topics

• Adolescent
• Adult
• Age of Onset
• Antihypertensive Agents (administration & dosage)
• Child
• Female
• Fibrosis (prevention & control)
• Follow-Up Studies
• Glaucoma (physiopathology, surgery)
• Humans
• Intraocular Pressure (physiology)
• Intraoperative Complications
• Male
• Middle Aged
• Molteno Implants
• New Zealand
• Postoperative Complications
• Prospective Studies
• Prosthesis Implantation
• Treatment Outcome
• Visual Acuity (physiology)