Births using sperm retrieved via immediate microdissection of a solitary testis with cancer.

Abstract

OBJECTIVE:

To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.

DESIGN:

Prospective clinical study of azoospermic men with testis cancer in a solitary testis.

SETTING:

Infertility patients in an academic environment.

PATIENT(S):

Azoospermic men with previous history of orchiectomy and testis cancer in a remaining solitary testis.

INTERVENTION(S):

Viable sperm were retrieved by immediate microdissection of paratumor testicular tissue from orchiectomy specimen.

MAIN OUTCOME MEASURE(S):

Live births were achieved using sperm from immediate microdissection of orchiectomy specimen with testis cancer.

CONCLUSION(S):

Azoospermic men with cancer in a solitary testis have potential for fertility.

• Authors: Benjamin B Choi, Marc Goldstein, Maureen Moomjy, Gianpiero Palermo, Zev Rosenwaks, Peter N Schlegel
• Journal: Fertility and sterility (Fertil Steril) Vol. 84 Issue 5 Pg. 1508 (Nov 2005) ISSN: 1556-5653 [Electronic] United States
• PMID: 16275252 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Humans
• Live Birth
• Male
• Microdissection (methods)
• Pregnancy
• Spermatozoa (cytology)
• Testicular Neoplasms (pathology, surgery)
• Testis (pathology, surgery)