Abstract | STUDY OBJECTIVES: DESIGN: Randomized controlled trial. SETTING: Cardiac surgery unit at a university hospital. PATIENTS: A total of 50 patients undergoing elective CABG surgery. INTERVENTION: MEASUREMENTS AND RESULTS: The overall incidence of episodic hypoxemia was 56% (28 of 50 patients) on the second postoperative night and 89% (41 of 46 patients) on the third postoperative night. More than 30 episodes of hypoxemia developed on the second night in 22% of patients (11 of 50 patients), and on the third night in 30% of patients (14 of 46 patients). Despite oxygen therapy, 7% of patients (3 of 46 patients) experienced constant hypoxemia on the third night. In general, hypoxemia seemed to be slightly worse on the third postoperative night compared with the second postoperative night. Significantly more patients in the TEA group (25 of 25 patients) experienced episodic hypoxemia on the third postoperative night compared with the CON group (16 of 21 patients; p < 0.05). Otherwise, there were no significant differences between the two regimens. CONCLUSIONS:
|
Authors | Lars Hyldborg Lundstrøm, Eigil Nygård, Lamia Bada Hviid, Finn Møller Pedersen, Jesper Ravn, Jan Aldershvile, Jacob Rosenberg |
Journal | Chest
(Chest)
Vol. 128
Issue 3
Pg. 1564-70
(Sep 2005)
ISSN: 0012-3692 [Print] United States |
PMID | 16162759
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Analgesics, Opioid
- Anesthetics, Local
- Morphine
- Bupivacaine
|
Topics |
- Aged
- Analgesia, Epidural
(adverse effects)
- Analgesics, Opioid
(adverse effects)
- Anesthetics, Local
(adverse effects)
- Bupivacaine
(adverse effects)
- Coronary Artery Bypass
- Humans
- Hypoxia
(chemically induced)
- Middle Aged
- Morphine
(adverse effects)
- Thoracic Vertebrae
- Time Factors
|