Nonoccupational determinants of plasma DDT and p,p'-DDE in men from Chiapas, Mexico.

Abstract

A cross-sectional study was conducted to evaluate nonoccupational biological exposure to 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) compounds and to identify the main factors associated with such exposure in a malaria endemic region in Mexico. Capillary gas column chromatography was used to determine levels of p,p'-DDT and its metabolites in plasma. The mean age of the 144 male participants was 28 yr. Mean p,p'-DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene) and p,p'-DDT levels were 203.5 microg/l and 67.4 microg/l, respectively. Those whose houses had been sprayed for malaria control had much higher p,p'-DDE levels (p < 0.001). High levels of chlorinated pesticides were found despite being banned in Mexico for agricultural and public health use. Findings demonstrate the role of antimalarial campaigns as a major contributing factor for high DDT plasma levels.

• Authors: Albino Barraza-Villarreal, Paulina Farías, Vicente Díaz Sánchez, Janice L Bailey, Tiaan De Jager, Pierre Ayotte, Mauricio Hernández-Avila, Eric Dewailly
• Journal: Archives of environmental health (Arch Environ Health) Vol. 59 Issue 1 Pg. 42-9 (Jan 2004) ISSN: 0003-9896 [Print] United States
• PMID: 16053209 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Insecticides
• Dichlorodiphenyl Dichloroethylene
• DDT

Topics

• Adult
• Chromatography, Gas
• Cross-Sectional Studies
• DDT (blood)
• Dichlorodiphenyl Dichloroethylene (blood)
• Endemic Diseases (prevention & control)
• Environmental Exposure (analysis)
• Humans
• Insecticides (blood)
• Malaria (prevention & control)
• Male
• Mexico (epidemiology)
• Mosquito Control (methods)