Abstract | BACKGROUND: The weight loss surgically induced by gastroplasty or gastric banding has only a transitory effect on the arterial hypertension of the severely obese patients, and a prevalence of hypertension similar to that of controls has been reported 8 years after the operation. METHODS: We studied the effects of biliopancreatic diversion in a series of 73 severely obese patients with preoperative hypertension throughout a 10-year follow-up period. Body weight dropped from 135.5 kg to 84.8 kg and remained substantially unchanged during the entire 10-year period, hypertension resolved in 41 subjects within the first postoperative year and the resolution rate increased slightly and progressively with time: at 10 years only 15 subjects were still hypertensive. Mean systolic and diastolic blood pressure (BP) value decreased within the first postoperative year as well as the pulse pressure (mean +/- standard deviation from 168 +/- 25 to 143 +/- 22 mm Hg, from 105 +/- 18 to 88 +/- 13 mm Hg, and from 65 +/- 16 to 50 +/- 13 mm Hg, respectively) and remained essentially unchanged throughout all the follow-up; 10 years after surgery the systolic BP and pulse pressure values (127 +/- 14 mm Hg and 42 +/- 6 mm Hg, respectively) were significantly lower than those observed at shorter term. CONCLUSIONS:
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Authors | Gianfranco Adami, Federica Murelli, Flavia Carlini, Francesco Papadia, Nicola Scopinaro |
Journal | American journal of hypertension
(Am J Hypertens)
Vol. 18
Issue 6
Pg. 780-4
(Jun 2005)
ISSN: 0895-7061 [Print] United States |
PMID | 15925736
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Adult
- Biliopancreatic Diversion
- Body Mass Index
- Disease Progression
- Female
- Follow-Up Studies
- Humans
- Hypertension
(complications, physiopathology)
- Male
- Middle Aged
- Obesity, Morbid
(complications, physiopathology)
- Postoperative Period
- Retrospective Studies
- Risk Factors
- Time Factors
- Treatment Outcome
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