Photoselective vaporization of the prostate: the basel experience after 108 procedures.

Abstract

OBJECTIVES:

This study aims to investigate safety and efficacy of 80 watt high-power potassium titanyl phosphate (KTP) laser vaporization of the prostate in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).

METHODS:

108 patients underwent 80W KTP laser vaporization. Functional follow-up included measurement of maximum urinary flow rate (Qmax), postvoid residual volume (Vres) and International Prostate Symptom Score (IPSS) within a 12 months period.

RESULTS:

The average prostate volume was 52.2+/-24.3 ml and the preoperative PSA value was 3.6+/-3.6 ng/dl. Mean operation time was 54.5+/-25.0 min. Qmax increased highly significantly (p<0.001) by 111% (+7.9 ml/s) at discharge, 212% (+15.1 ml/s) after three months, 201% (+14.3 ml/s) after six months and 252% (+17.9 ml/s) after 12 months. Correspondingly, Vres, IPSS and Bother Score improved to an extent that was statistically highly significant (p<0.001) immediately after surgery. The observed complication rate within one year was low.

CONCLUSIONS:

80 W KTP laser vaporization is a virtually bloodless, safe and effective procedure for surgical treatment of LUTS secondary to BPH. A significant improvement of objective and subjective voiding parameters was observed just after surgery. KTP laser vaporization is associated with a low rate of complications.

• Authors: Alexander Bachmann, Robin Ruszat, Stephen Wyler, Oliver Reich, Helge H Seifert, Alexander Müller, Tullio Sulser
• Journal: European urology (Eur Urol) Vol. 47 Issue 6 Pg. 798-804 (Jun 2005) ISSN: 0302-2838 [Print] Switzerland
• PMID: 15925076 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Phosphates
• potassium titanylphosphate
• Titanium

Topics

• Aged
• Aged, 80 and over
• Follow-Up Studies
• Humans
• Laser Therapy
• Male
• Middle Aged
• Phosphates
• Prostatic Hyperplasia (complications, surgery)
• Retrospective Studies
• Safety
• Titanium
• Treatment Outcome
• Urination Disorders (etiology, physiopathology, surgery)
• Urodynamics
• Urologic Diseases