[Effect of bilirubin on serum fructosamine value, and the elimination of bilirubin by bilirubin oxidase].

Abstract

Fructosamine is examined as the index of past mean blood glucose levels. However, the fructosamine value appears to be influenced by the bilirubin. Therefore, we examined patients with hyperbilirubinemia showing suspected and definite jaundice. Abnormal fructosamine values were noted in 9 out of the 50 cases (18%) with suspected jaundice and 40 out of the 55 cases (72.2%) with definite jaundice. An experiment in which bilirubin was removed by bilirubin oxidase revealed that fructosamine levels in hyperbilirubinemia correlated with the values of bilirubin and increased fructosamine values were expressed as the values of bilirubin x 6.5. These results demonstrate abnormal fructosamine values not only in jaundice patients but also in those with suspected jaundice. These cases must be taken in the examination of fructosamine in patients with hyperbilirubinemia.

• Authors: Y Ohisa, T Kawamura, Y Abe, A Ishimori
• Journal: Rinsho byori. The Japanese journal of clinical pathology (Rinsho Byori) Vol. 40 Issue 2 Pg. 194-8 (Feb 1992) ISSN: 0047-1860 [Print] Japan
• PMID: 1583793 (Publication Type: English Abstract, Journal Article)

Chemical References

• Hexosamines
• Fructosamine
• Oxidoreductases
• Oxidoreductases Acting on CH-CH Group Donors
• bilirubin oxidase
• Bilirubin

Topics

• Bilirubin
• Fructosamine
• Hexosamines (blood)
• Humans
• Hyperbilirubinemia (blood)
• Jaundice (blood, diagnosis)
• Oxidoreductases
• Oxidoreductases Acting on CH-CH Group Donors