Gadolinium encephalopathy in a patient with renal failure.

Abstract

Gadolinium chelates are extensively used in MRI studies. Neurotoxicity due to gadolinium chelates is minimal and uncommon. A 57-year-old woman in renal failure developed a subacute encephalopathy after inadvertent repetitive gadolinium contrast administration. An unusual MRI appearance with CSF hyperintensity due to gadolinium diffusion into the CSF is also shown.

• Authors: Boby Varkey Maramattom, Edward M Manno, Eelco F M Wijdicks, Edward P Lindell
• Journal: Neurology (Neurology) Vol. 64 Issue 7 Pg. 1276-8 (Apr 12 2005) ISSN: 1526-632X [Electronic] United States
• PMID: 15824364 (Publication Type: Case Reports, Journal Article)

Chemical References

• Gadolinium

Topics

• Amnesia, Retrograde (etiology)
• Brain (drug effects, metabolism, pathology)
• Brain Diseases, Metabolic (cerebrospinal fluid, chemically induced, physiopathology)
• Causality
• Cerebrospinal Fluid (chemistry, drug effects)
• Consciousness Disorders (cerebrospinal fluid, chemically induced, physiopathology)
• Female
• Gadolinium (pharmacokinetics, poisoning)
• Humans
• Hypertension (complications, diagnosis, physiopathology)
• Magnetic Resonance Imaging
• Metabolic Clearance Rate (physiology)
• Middle Aged
• Patient Selection
• Recovery of Function
• Renal Insufficiency (complications, metabolism, physiopathology)