Clinical comparison of locetamic acid (cholebrine) and ipodate sodium (Orgrafin).

Abstract	Locetamic acid (Cholebrine) and ipodate sodium (Oragrafin) were compared in a double blind study of 503 patients. The radiographs were evaluated for contrast density, visualization of common duct, gallstones, residual in the intestinal tract, and side effects. Cholebrine demonstrated better opacification, fewer repeat examinations, slightly greater common duct opacification, and more frequent visualization of gallstones. Oragrafin had less residue. Side effects were minimal with both contrast agents.
Authors	R R Neal, K G Harvey, K G Cantwell, H C Press Jr
Journal	AJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 132 Issue 5 Pg. 735-6 (May 1979) ISSN: 0361-803X [Print] United States
PMID	155391 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References	Iodobenzenes Ipodate
Topics	Administration, Oral Cholecystography (methods) Clinical Trials as Topic Double-Blind Method Drug Evaluation Humans Iodobenzenes (administration & dosage, adverse effects) Ipodate (administration & dosage, adverse effects) Nausea (chemically induced) Vomiting (chemically induced)

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