The androgen insensitive micropenis: long-term follow-up into adulthood.

Abstract

AIM:

To assess the adult stretched penile length (SPL) and sexuality in patients with micropenis who exhibited an inadequate response to exogenous testosterone therapy and were raised as males.

PATIENTS AND METHODS:

Patients with micropenis who had an equivocal response to exogenous testosterone therapy and were raised as males were evaluated at adulthood (>17 yr).

RESULTS AND CONCLUSIONS:

Twenty patients with micropenis, initial median SPL -3.3 SD below the mean (range -5.5 to -2.6) had a suboptimal response to initial testosterone therapy, median SPL post-treatment -2.7 SD (-3.3 to -2.2), and were raised as males. At adulthood, 90% (18/20) had a micropenis, median SPL -3.4 (-5.9 to -2.2). All have a male gender identity, five are undergoing psychiatric counseling (fear of sexual rejection--five patients, one of whom also has suicidal ideation). Eight have not pursued a sexual relationship; 12 are sexually active, one of whom is bisexual.

• Authors: D A Husmann
• Journal: Journal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) Vol. 17 Issue 8 Pg. 1037-41 (Aug 2004) ISSN: 0334-018X [Print] Germany
• PMID: 15379413 (Publication Type: Journal Article)

Chemical References

• Testosterone

Topics

• Adolescent
• Adult
• Child
• Child, Preschool
• Follow-Up Studies
• Gender Identity
• Humans
• Hypogonadism (drug therapy, psychology)
• Infant
• Male
• Penis (abnormalities, growth & development)
• Sexuality (physiology, psychology)
• Testosterone (therapeutic use)
• Treatment Outcome