Neuroendocrine protein 7B2 in Prader-Willi syndrome.

Abstract

7B2 is a neuroendocrine polypeptide of unknown function, the gene for which is sited near or within the chromosomal region deleted in Prader-Willi syndrome and Angelman's syndrome. Plasma immunoreactive 7B2 levels were measured in 26 individuals with Prader-Willi syndrome, and appropriate controls. Plasma 7B2 levels were within normal limits compared to the control groups, in adults with Prader-Willi syndrome. 7B2 levels in children with Prader-Willi syndrome were higher, this age-dependent variation having been previously reported in normal children.

• Authors: D A Graham, G D Abbott, Y Suzuki, H Suzuki, S Shimoda
• Journal: Australian and New Zealand journal of medicine (Aust N Z J Med) Vol. 22 Issue 5 Pg. 455-7 (Oct 1992) ISSN: 0004-8291 [Print] Australia
• PMID: 1445035 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Nerve Tissue Proteins
• Neuroendocrine Secretory Protein 7B2
• Pituitary Hormones
• SCG5 protein, human

Topics

• Adolescent
• Age Factors
• Child
• Chromosome Deletion
• Female
• Humans
• Karyotyping
• Male
• Middle Aged
• Nerve Tissue Proteins
• Neuroendocrine Secretory Protein 7B2
• Neurosecretory Systems (metabolism)
• Pituitary Hormones (blood)
• Prader-Willi Syndrome (blood, genetics)