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URACIL MUSTARD: A POTENT INDUCER OF LUNG TUMORS IN MICE.

Abstract
Uracil mustard, injected intraperitoneally, increased the incidence and average number of pulmonary tumors in A/J mice. In comparison to a typical alkylating agent, nitrogen mustard, or to urethan, uracil mustard (on a molar basis) was considerably more carcinogenic.
AuthorsC W ABELL, H L FALK, M B SHIMKIN, E K WEISBURGER, J H WEISBURGER, N GUBAREFF
JournalScience (New York, N.Y.) (Science) Vol. 147 Issue 3664 Pg. 1443-5 (Mar 19 1965) ISSN: 0036-8075 [Print] United States
PMID14268720 (Publication Type: Journal Article)
Chemical References
  • Nitrogen Mustard Compounds
  • Urethane
  • Mechlorethamine
  • RNA
  • DNA
  • Uracil Mustard
Topics
  • DNA
  • Lung Neoplasms
  • Mechlorethamine
  • Mice
  • Neoplasms
  • Neoplasms, Experimental
  • Nitrogen Mustard Compounds
  • Pharmacology
  • RNA
  • Research
  • Toxicology
  • Uracil Mustard
  • Urethane

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