Human gastric lipase: ontogeny and variations in children.

Abstract

The aim of this study was to investigate the precise origin of the acid pre-duodenal lipase during human development and to evaluate its possible changes, at the tissue level, in children with gastritis or pancreatic insufficiency. Human gastric lipase appears around the 11th week of gestation and increases slowly during pre- and postnatal development. It is localized in the fundus of the stomach without any lingual localization. Human gastric lipase reaches its adult level in the third month of life, and does not vary in relation to pancreatic insufficiency. It is only rarely impaired during gastritis.

• Authors: J Sarles, H Moreau, R Verger
• Journal: Acta paediatrica (Oslo, Norway : 1992) (Acta Paediatr) 1992 Jun-Jul Vol. 81 Issue 6-7 Pg. 511-3 ISSN: 0803-5253 [Print] Norway
• PMID: 1392363 (Publication Type: Journal Article)

Chemical References

• Lipase

Topics

• Adolescent
• Child
• Child, Preschool
• Cystic Fibrosis (complications, enzymology)
• Exocrine Pancreatic Insufficiency (enzymology, etiology)
• Fetus (enzymology)
• Gastric Mucosa (enzymology)
• Gastritis (enzymology)
• Gastroesophageal Reflux (enzymology)
• Humans
• Infant
• Infant, Newborn (physiology)
• Lipase (analysis)