Prostatic abscess in southern Taiwan: another invasive infection caused predominantly by Klebsiella pneumoniae.

Abstract

Prostatic abscess, though rarely encountered since the introduction of broad-spectrum antibiotics, can cause significant morbidity and mortality. We retrospectively reviewed 17 cases of prostatic abscess treated during an 11-year period at 2 medical centers in southern Taiwan. Most of these patients were elderly (mean age, 59 years) with diabetes mellitus (10 cases, 59%) or hepatic cirrhosis (5 cases, 29%). Fourteen (82%) of the 17 patients were febrile, with chills occurring in about a half of these. Of the symptoms and signs referable to the lower urinary tract, dysuria (71%) was the most common complaint. Pain was usually localized in the suprapubic (35%) or perineal (18%) area. The common findings of digital rectal examination were prostatic enlargement (77%) and fluctuation (23%). Prostatic abscess was impressed from the findings of hypoechoic area with thick walls on transrectal ultrasound or an enlarged gland with fluid-density collections on computed tomography. All causative pathogens were gram-negative bacilli, including Klebsiella pneumoniae (10 cases), Escherichia coli (2), and Pseudomonas aeruginosa (1). Various measures were undertaken to allow drainage, including transurethral incision or resection of the prostate, open perineal incision, laparotomy, and transrectal ultrasound- or computed tomography-guided needle aspiration. In conclusion, K. pneumoniae was the predominant pathogen of prostatic abscess, and was frequently identified as the causative pathogen in patients with diabetes mellitus. Diagnosis of prostatic abscess based merely on symptomatology is implausible, and image studies, such as transrectal ultrasound or computed tomography scan, are warranted. Optimal management includes adequate drainage of abscess and antimicrobial therapy.

• Authors: Kung-Hung Liu, Hsin-Chun Lee, Yin-Ching Chuang, Chang-An Tu, Ko Chang, Nan-Yao Lee, Wen-Chien Kos
• Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi (J Microbiol Immunol Infect) Vol. 36 Issue 1 Pg. 31-6 (Mar 2003) ISSN: 1684-1182 [Print] England
• PMID: 12741730 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Abscess (microbiology)
• Adult
• Aged
• Aged, 80 and over
• Anti-Bacterial Agents (therapeutic use)
• Diabetes Complications
• Escherichia coli (isolation & purification)
• Escherichia coli Infections (microbiology)
• Humans
• Klebsiella Infections (microbiology)
• Klebsiella pneumoniae (isolation & purification)
• Male
• Middle Aged
• Prostatic Diseases (diagnosis, drug therapy, microbiology, physiopathology)
• Pseudomonas Infections (microbiology)
• Pseudomonas aeruginosa (isolation & purification)
• Retrospective Studies
• Taiwan