Atypical teratoid/rhabdoid tumors.

Abstract

CASE REPORTS:

We describe three cases of atypical ATRT that were identified at the Children's Hospital of Eastern Ontario.

DISCUSSION:

Over the past decade, atypical teratoid/rhabdoid tumors (ATRTs) of the central nervous system have emerged as a distinct entity. This tumor is typically misdiagnosed as a primitive neuroectodermal tumor (PNET)/medulloblastoma. The unique immunohistochemistry profile of an ATRT helps distinguish it from a PNET/medulloblastoma. This is of clinical importance because the prognosis of a patient with an ATRT is worse than that of a PNET/medulloblastoma despite aggressive surgical treatment with or without adjuvant chemotherapy and radiation therapy.

• Authors: Tommy Dang, Michael Vassilyadi, Jean Michaud, Carmencita Jimenez, Enrique C G Ventureyra
• Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (Childs Nerv Syst) Vol. 19 Issue 4 Pg. 244-8 (Apr 2003) ISSN: 0256-7040 [Print] Germany
• PMID: 12682757 (Publication Type: Case Reports, Journal Article)

Topics

• Brain Neoplasms (diagnostic imaging, pathology, therapy)
• Child, Preschool
• Diagnosis, Differential
• Female
• Humans
• Immunohistochemistry
• Infant
• Magnetic Resonance Imaging
• Male
• Medulloblastoma (diagnosis)
• Prognosis
• Rhabdoid Tumor (diagnostic imaging, pathology, therapy)
• Teratoma (diagnostic imaging, pathology, therapy)
• Tomography, X-Ray Computed
• Treatment Outcome