Monoclonal antibodies in immune and inflammatory diseases.

Abstract

The era of monoclonal antibody-based therapeutics has arrived. Monoclonal antibodies of high quality targeting almost any antigen can now be engineered and manufactured in large quantities. In the clinic, monoclonal antibodies are proving to be safe and effective for the treatment of a wide range of diseases including rheumatoid arthritis, Crohn's disease, spondyloarthropathies, psoriasis and allograft rejection.

• Authors: Evangelos Andreakos, Peter C Taylor, Marc Feldmann
• Journal: Current opinion in biotechnology (Curr Opin Biotechnol) Vol. 13 Issue 6 Pg. 615-20 (Dec 2002) ISSN: 0958-1669 [Print] England
• PMID: 12482523 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Antibodies, Monoclonal

Topics

• Antibodies, Monoclonal (therapeutic use)
• Arthritis, Rheumatoid (therapy)
• Autoimmune Diseases (therapy)
• Autoimmune Diseases of the Nervous System
• Child
• Clinical Trials as Topic
• Crohn Disease (therapy)
• Drug Approval
• Graft Rejection (prevention & control)
• Humans
• Immunotherapy, Active (methods)
• Inflammation (therapy)