[Pitfalls and precautions concerning the use of conventional oral antidiabetic drugs].

Abstract

The main pitfalls regarding the use of sulphonylureas and metformin in type 2 diabetic patients are described and illustrated by a clinical case. Advices are given in order to avoid the occurrence of severe hypoglycaemic episodes with sulphonylureas and to minimise the risk of lactic acidosis with metformin. These drugs, when used appropriately with respect of contra-indications, have an excellent safety profile and remain the basis of the treatment of type 2 diabetes.

• Authors: A J Scheen
• Journal: Revue medicale de Liege (Rev Med Liege) Vol. 57 Issue 5 Pg. 352-6 (May 2002) ISSN: 0370-629X [Print] Belgium
• Vernacular Title: Pièges et conseils à propos de l'utilisation des antidiabétiques oraux conventionnels.
• PMID: 12143186 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Hypoglycemic Agents
• Sulfonylurea Compounds
• Metformin

Topics

• Acidosis, Lactic (etiology, prevention & control)
• Administration, Oral
• Aged
• Diabetes Mellitus, Type 2 (drug therapy)
• Humans
• Hypoglycemia (drug therapy, etiology)
• Hypoglycemic Agents (adverse effects, therapeutic use)
• Male
• Metformin (adverse effects, therapeutic use)
• Sulfonylurea Compounds (adverse effects, therapeutic use)