Abstract |
Various evaluation methods are available for aiding clinicians in lung cancer management. Some of these methods are highly specific. However, they are also invasive and burdened by non-negligible complication rates (e.g., mediastinoscopy); other methods are highly accurate and noninvasive, but require expensive equipment and well-trained personnel (e.g., PET scanning); others are fast, inexpensive and safe. However, their diagnostic yield is low and requires further clinical testing (an example of such tests is the chest- x-ray film). There is probably only one way to perform an easy, inexpensive, repeatable test, which is also fairly accurate and predictive. This is tumor marker testing, which--as a large and specialized literature shows--can be highly effective when based on a cytokeratin-derived marker assay.
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Authors | G Buccheri, D Ferrigno |
Journal | Expert review of molecular diagnostics
(Expert Rev Mol Diagn)
Vol. 1
Issue 3
Pg. 315-22
(Sep 2001)
ISSN: 1473-7159 [Print] England |
PMID | 11901837
(Publication Type: Journal Article, Review)
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Chemical References |
- Antigens, Neoplasm
- Biomarkers, Tumor
- Keratin-19
- antigen CYFRA21.1
- Keratins
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Topics |
- Antigens, Neoplasm
(genetics)
- Biomarkers, Tumor
- Dose-Response Relationship, Drug
- Humans
- Keratin-19
- Keratins
(genetics)
- Lung Neoplasms
(diagnosis, genetics)
- Molecular Diagnostic Techniques
- Sensitivity and Specificity
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