[Investigation on skin retrograde degeneration after tissue expansion].

Abstract

OBJECTIVE:

To study the effects of tissue expansion on tissue damage and retrograde degeneration.

METHODS:

9 cases of conventional intermittent tissue expansion (CITE) and 9 cases of continuous pressure-controlled tissue expansion (CPTE) were chosen for the study. In creating of the expanded flaps, tissue samples were taken for histopathology, molecular biology and transmission electron microscope (TEM) examinations.

RESULTS:

Capillary bleeding, elastic and reticular fiber proliferation, arteriole thrombosis, fibroblast apoptosis and collagenolysis were observed after expansion. Retrograde degeneration was obvious in CITE group and acute lesion was obvious in CPTE group.

CONCLUSION:

Expansion stimulation induces tissue damage and retrograde degeneration, which indicates that the time for conventional intermittent expansion should be shortened and too fast continuous expansion is harmful.

• Authors: J Li, K Lu, Y Ai
• Journal: Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery (Zhonghua Zheng Xing Wai Ke Za Zhi) Vol. 17 Issue 6 Pg. 347-9 (Nov 2001) ISSN: 1009-4598 [Print] China
• PMID: 11838058 (Publication Type: English Abstract, Journal Article)

Topics

• Humans
• Retrograde Degeneration
• Skin (innervation, pathology)
• Tissue Expansion