Effect of the antiulcer polysaccharide fraction from Bupleurum falcatum L. on the healing of gastric ulcer induced by acetic acid in rats.

Abstract

An antiulcer polysaccharide fraction (BR-2) from Bupleurum falcatum L. was examined for its effect on the healing of chronic ulcers induced by acetic acid in rats. When BR-2 was administered orally to the rats, it was shown to be effective in the healing of acetic acid-induced chronic ulcer. This result suggests that the use of herbal prescriptions containing B. falcatum L. may prove useful for the treatment of peptic ulcers.

• Authors: T Matsumoto, X B Sun, T Hanawa, H Kodaira, K Ishii, H Yamada
• Journal: Phytotherapy research : PTR (Phytother Res) Vol. 16 Issue 1 Pg. 91-3 (Feb 2002) ISSN: 0951-418X [Print] England
• PMID: 11807976 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright 2002 John Wiley & Sons, Ltd.

Chemical References

• Anti-Ulcer Agents
• Plant Extracts
• Polysaccharides
• Acetic Acid

Topics

• Acetic Acid (toxicity)
• Animals
• Anti-Ulcer Agents (pharmacology, therapeutic use)
• Bupleurum
• Dose-Response Relationship, Drug
• Gastric Mucosa (drug effects, pathology)
• Male
• Peptic Ulcer (chemically induced, drug therapy)
• Phytotherapy
• Plant Extracts (pharmacology, therapeutic use)
• Plant Roots (chemistry)
• Polysaccharides (isolation & purification, pharmacology)
• Rats
• Rats, Wistar