Abstract | PURPOSE: METHODS: In 1982, BMT was successfully performed on a 13-year-old girl with MLS with growth retardation, typical facial features, skeletal and joint deformities, hepatosplenomegaly, cardiopulmonary dysfunction, and corneal clouding. Corneal transplantation was done on the left eye in 1986, and on the right eye in 1987 (6 months later) without difficulty or complication. RESULTS: Thirteen years postoperatively, the patient was systemically well, and both eyes retained clear corneal grafts. CONCLUSION: BMT retarded further dysfunction from MLS, and the corneal transplants retained clarity. Further controlled studies with longer follow-up are required to establish the efficacy of BMT in ocular manifestations of MPS or MLS.
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Authors | O O Uçakhan, S E Brodie, R Desnick, J Willner, P A Asbell |
Journal | The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc
(CLAO J)
Vol. 27
Issue 4
Pg. 234-7
(Oct 2001)
ISSN: 0733-8902 [Print] United States |
PMID | 11725989
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Adult
- Bone Marrow Transplantation
- Cornea
(physiology)
- Corneal Opacity
(physiopathology, surgery)
- Female
- Follow-Up Studies
- Graft Survival
(physiology)
- Humans
- Keratoplasty, Penetrating
(physiology)
- Mucopolysaccharidosis VI
(therapy)
- Visual Acuity
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