Snuff dippers keratosis (snuff-induced leukoplakia).

Abstract

Patients with chronic snuff-induced keratosis associated with mucosal ulcerations were treated with topically applied vitamin A acid. In each case, after a marked, local inflammatory response initially, topical vitamin A acid showed a definite beneficial effect in promoting healing and involution of the precancerous snuff-induced leukoplakic keratosis. In one patient there was distinct involution of the oral lesions with complete healing and restoration of a normal-appearing mucosa within five weeks after beginning of treatment. In four patients there was healing of superficial ulcerations and regression in the size of the luekoplakic lesions.

• Authors: C J Raque, R V Biondo, M G Keeran, W M Honeycutt, G T Jansen
• Journal: Southern medical journal (South Med J) Vol. 68 Issue 5 Pg. 565-8 (May 1975) ISSN: 0038-4348 [Print] United States
• PMID: 1168946 (Publication Type: Journal Article)

Chemical References

• Vitamin A

Topics

• Aged
• Cheek
• Chronic Disease
• Female
• Humans
• Leukoplakia, Oral (chemically induced, drug therapy, pathology, surgery)
• Male
• Middle Aged
• Mouth Mucosa (drug effects)
• Plants, Toxic
• Tobacco
• Tobacco, Smokeless
• Vitamin A (therapeutic use)