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Toxicant-induced oxidative stress in cancer.

Abstract
The article highlighted in this issue is "The Role of Oxidative Stress in Indium Phosphide-Induced Lung Carcinogenesis in Rats" by Barbara C. Gottschling, Robert R. Maronpot, James R. Hailey, Shyamal Peddada, Cindy R. Moomaw, James E. Klaunig, and Abraham Nyska (pp. 28-40). The article integrates a traditional pathologic study of toxicant-induced pulmonary carcinogenesis with an immunohistologic assessment of oxidative stress, thereby determining a potential mechanism of action of a toxicant, specifically indium phosphide.
AuthorsB L Upham, J G Wagner
JournalToxicological sciences : an official journal of the Society of Toxicology (Toxicol Sci) Vol. 64 Issue 1 Pg. 1-3 (Nov 2001) ISSN: 1096-6080 [Print] United States
PMID11606793 (Publication Type: Journal Article, Comment)
Chemical References
  • Biomarkers
  • Oxidants
  • Phosphines
  • Indium
  • indium phosphide
Topics
  • Animals
  • Biomarkers
  • Humans
  • Indium (toxicity)
  • Lung Neoplasms (chemically induced, metabolism)
  • Oxidants (metabolism)
  • Oxidative Stress
  • Phosphines (toxicity)

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