Photosensitivity induced by oral itraconazole.

Abstract

A case of photosensitivity induced by itraconazole is reported. A 70-year-old woman had erythema, oedema and vesicles on sun-exposed areas after 5 days of itraconazole treatment for oral candidiasis. Oral photochallenge using itraconazole and sun irradiation was positive, but photopatch test was negative. Photosensitivity from azoles is an uncommon adverse effect. Only three other cases have been described, two induced by ketoconazole and one by itraconazole.

• Authors: J G Alvarez-Fernández, E Castaño-Suárez, P Cornejo-Navarro, E G de la Fuente, F J Ortiz de Frutos, L Iglesias-Diez
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 14 Issue 6 Pg. 501-3 (Nov 2000) ISSN: 0926-9959 [Print] England
• PMID: 11444275 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Itraconazole

Topics

• Aged
• Antifungal Agents (administration & dosage, adverse effects)
• Candidiasis, Oral (diagnosis, drug therapy)
• Dermatitis, Photoallergic (diagnosis, etiology)
• Female
• Follow-Up Studies
• Humans
• Itraconazole (adverse effects, therapeutic use)
• Risk Assessment