[Use of cefuroxime axetil in clinical practice].

Abstract

This study summarizes the actual recommendations for cefuroxime axetil treatment in dermatology and general medicine. These include the well known clinical efficacies in therapy of upper and lower respiratory tract infections, genitourinary tract infections and skin and soft tissue infections, but also connective tissue diseases, such as morphea and SCLE. Though the immunomodulatory activity of the drug should be established by further controlled studies, there are some limited literature data, which show the modulatory effect of cefuroxime axetil on the lymphocyte proliferation and the production of selected cytokines.

• Authors: M Słowińska, E Szymańska, I Walecka, L Rudnicka
• Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego (Pol Merkur Lekarski) Vol. 9 Issue 53 Pg. 785-90 (Nov 2000) ISSN: 1426-9686 [Print] Poland
• Vernacular Title: Zastosowanie aksetylu cefuroksymu w praktyce klinicznej.
• PMID: 11204332 (Publication Type: Journal Article, Review)

Chemical References

• Cytokines
• Cefuroxime
• cefuroxime axetil

Topics

• Bacterial Infections (drug therapy)
• Borrelia Infections (drug therapy)
• Cefuroxime (analogs & derivatives, pharmacology, therapeutic use)
• Connective Tissue Diseases (drug therapy)
• Cytokines (biosynthesis, drug effects)
• Dermatitis (drug therapy)
• Humans
• Lymphocytes (drug effects)
• Respiratory Tract Infections (drug therapy)