Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations during pregnancy.

Abstract

STUDY OBJECTIVES:

To determine if transcatheter embolotherapy is safe and effective for the treatment of pulmonary arteriovenous malformations during pregnancy.

DESIGN:

Prospective study.

SETTING:

Specialized hereditary hemorrhagic telangiectasia centers at Yale University School of Medicine and St. Michael's Hospital, University of Toronto.

PATIENTS:

Seven pregnant women (age range, 24 to 34 years; gestational age range, 16 to 36 weeks) undergoing transcatheter embolotherapy.

INTERVENTIONS:

Transcatheter embolotherapy in all patients.

MEASUREMENTS AND RESULTS:

Thirteen pulmonary arteriovenous malformations in seven patients were embolized with detachable silicone balloons and/or stainless steel coils without incident. The estimated fetal radiation dose ranged from < 50 to 220 mrad. No complications of pulmonary arteriovenous malformations occurred in any of the patients after transcatheter embolotherapy. The mothers went on to deliver healthy babies in all cases.

CONCLUSIONS:

Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations performed by an experienced radiologist appears to be safe and effective after 16 weeks of gestational age.

• Authors: A S Gershon, M E Faughnan, K S Chon, R A Pugash, J A Clark, M J Bohan, K J Henderson, R H Hyland, R I White Jr
• Journal: Chest (Chest) Vol. 119 Issue 2 Pg. 470-7 (Feb 2001) ISSN: 0012-3692 [Print] United States
• PMID: 11171725 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adult
• Arteriovenous Malformations (therapy)
• Embolization, Therapeutic
• Female
• Humans
• Pregnancy
• Pregnancy Complications, Cardiovascular (therapy)
• Pulmonary Artery (abnormalities)
• Pulmonary Veins (abnormalities)