Abstract | BACKGROUND: Endogenous production of nitric oxide and its presence in exhaled air was observed in humans. Prior studies have yielded contrasting information about the production of nitric oxide in patients with heart failure. AIMS: METHODS: Seventy-four patients (6 patients had isolated mitral stenosis; 13 patients had combined mitral stenosis and mitral regurgitation; 1 patient had isolated mitral regurgitation; 54 patients had combined mitral and aortic valve disease) and 27 healthy subjects were entered in the study. The nitric oxide concentration in exhaled air was determined with a chemiluminescence analyser. Echocardiography was performed in all patients to assess the severity of the valve disease and for the measurement of pulmonary artery pressure. RESULTS: CONCLUSION:
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Authors | Z Gölbaşi, S Dinçer, H Bayol, B Uğurlu, D Ciçek, T Keleş, S Aydoğdu, D Erbaş |
Journal | European journal of heart failure
(Eur J Heart Fail)
Vol. 3
Issue 1
Pg. 27-32
(Jan 2001)
ISSN: 1388-9842 [Print] England |
PMID | 11163732
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Chi-Square Distribution
- Echocardiography
- Female
- Humans
- Hypertension, Pulmonary
(complications, diagnostic imaging, metabolism)
- Luminescent Measurements
- Lung
(metabolism)
- Male
- Middle Aged
- Nitric Oxide
(biosynthesis)
- Rheumatic Heart Disease
(complications, diagnostic imaging, metabolism)
- Statistics, Nonparametric
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