Peritoneal fluid concentrations of interleukin-11 in women with endometriosis.

Abstract

OBJECTIVE:

To determine the peritoneal fluid concentrations of interleukin-11 (IL-11) in women with endometriosis as compared with the control group.

DESIGN:

A prospective, controlled study.

SETTING:

The obstetrics and gynecology department of a teaching hospital and a university immunology department.

PATIENT(S):

Sixty consecutive women undergoing laparoscopic surgery for benign gynecological indications.

INTERVENTION(S):

Peritoneal fluid was obtained during laparoscopy, and the concentration of IL-11 was measured.

MAIN OUTCOME MEASURE(S):

Concentration of IL-11 in correlation with the presence of endometriosis, its stage, and the phase of the menstrual cycle.

RESULT(S):

IL-11 was detectable in the peritoneal fluid of 64% of women tested. Concentrations of IL-11 showed no correlation with the presence of endometriosis, the American Fertility Society stage of the disease, or the phase of the menstrual cycle.

CONCLUSION(S):

We found no evidence to suggest that IL-11 is involved in the pathogenesis of pelvic endometriosis.

• Authors: M R Gazvani, M Bates, G Vince, S Christmas, D I Lewis-Jones, C Kingsland
• Journal: Fertility and sterility (Fertil Steril) Vol. 74 Issue 6 Pg. 1182-6 (Dec 2000) ISSN: 0015-0282 [Print] United States
• PMID: 11119747 (Publication Type: Journal Article)

Chemical References

• Interleukin-11

Topics

• Adult
• Ascitic Fluid (metabolism)
• Endometriosis (metabolism, pathology, physiopathology)
• Female
• Humans
• Interleukin-11 (metabolism)
• Menstrual Cycle
• Osmolar Concentration
• Prospective Studies
• Reference Values