Abstract | BACKGROUND: METHODS AND RESULTS: A total of 40 patients with first anterior AMI were examined. All patients underwent primary balloon angioplasty or stenting within 12 h of the onset of AMI. No-reflow, defined as TIMI grade 2 flow or less without residual stenosis after angioplasty, was observed in 15 patients. Patients with no-reflow were older (67+/-9 vs. 58+/-10 years, P=0.006) and had a lower incidence of preinfarction angina (7% vs. 48%, P=0.01) than those without no-reflow. Patients with no-reflow had poorer LV function at predischarge and a higher incidence of pump failure, LV aneurysm, malignant ventricular arrhythmias or cardiac death during the hospital course in association with higher peak serum C-reactive protein levels (12.7+/-8.0 vs. 7.1+/-5.5 mg/dl, P=0.02). Multivariate analysis showed that the absence of preinfarction angina was a major independent determinant of no-reflow (RR=17.1, P=0.02). CONCLUSIONS: The absence of preinfarction angina is more frequently observed in patients with no-reflow. The beneficial effect of preinfarction angina on LV function may be explained, at least in part, by prevention of no-reflow after reperfusion.
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Authors | T Takahashi, T Anzai, T Yoshikawa, Y Asakura, S Ishikawa, H Mitamura, S Ogawa |
Journal | International journal of cardiology
(Int J Cardiol)
Vol. 75
Issue 2-3
Pg. 253-60
(Sep 15 2000)
ISSN: 0167-5273 [Print] Netherlands |
PMID | 11077143
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Angina Pectoris
(physiopathology)
- Angioplasty, Balloon, Coronary
- Coronary Angiography
- Coronary Circulation
- Humans
- Middle Aged
- Myocardial Infarction
(diagnostic imaging, physiopathology, therapy)
- Prognosis
- Ventricular Function, Left
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