Regulation of cardiac function in prepubertal rats.

Abstract

Prepubertal period in rats is characterized by some peculiarities of the cardiac regulatory mechanisms. In 6-week-old rats atropine produced bradycardia instead of tachycardia. Similar reaction was not observed in chemically sympathectomized age-matched rats.

• Authors: T L Zefirov, N V Svyatova, N I Ziyatdinova
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 129 Issue 6 Pg. 516-8 (Jun 2000) ISSN: 0007-4888 [Print] United States
• PMID: 11022235 (Publication Type: Journal Article)

Chemical References

• Adrenergic beta-Antagonists
• Muscarinic Antagonists
• Sympatholytics
• Atropine
• Propranolol
• Guanethidine

Topics

• Adrenergic beta-Antagonists (pharmacology)
• Animals
• Atropine (pharmacology)
• Electric Stimulation
• Electrocardiography
• Guanethidine (pharmacology)
• Heart (drug effects, innervation, physiology)
• Heart Rate (drug effects)
• Muscarinic Antagonists (pharmacology)
• Parasympathetic Nervous System (physiology)
• Propranolol (pharmacology)
• Rats
• Sexual Maturation
• Sympathectomy, Chemical
• Sympathetic Nervous System (physiology)
• Sympatholytics (pharmacology)
• Vagotomy
• Vagus Nerve (drug effects, metabolism)