3- (1,4- diazabicyclo(3.2.2)nonan- 4- yl)- 6- fluorodibenzo(b,d)thiophene 5,5-dioxide

12/20/2018 - "Methods: In this cross-sectional PET study, we used 18F-ASEM, a radiotracer targeting the α7-nAChR, with positron emission tomography to compare the binding of 18F-ASEM in hippocampus between individuals with recent-onset psychosis and healthy controls. "
12/20/2018 - "Results: Individuals with recent-onset psychosis [non-affective psychosis (NP) or affective psychosis], and particularly those with NP, showed lower hippocampal binding of 18F-ASEM than healthy controls. "
12/20/2018 - "The availability of the α7 nicotinic acetylcholine receptor in recent-onset psychosis: a study using 18F-ASEM PET."

01/01/2022 - "For PET of α7 nAChR, 18F-ASEM and 11C-MeQAA were successfully applied in mild cognitive impairment and AD, respectively. "
01/01/2020 - "High Availability of the α7-Nicotinic Acetylcholine Receptor in Brains of Individuals with Mild Cognitive Impairment: A Pilot Study Using 18F-ASEM PET."
01/01/2020 - "Methods: In this cross-sectional study, 14 patients with mild cognitive impairment (MCI), a prodromal stage to dementia, and 17 cognitively intact, elderly controls completed 18F-ASEM PET. "

01/01/2020 - "Methods: In this cross-sectional study, 14 patients with mild cognitive impairment (MCI), a prodromal stage to dementia, and 17 cognitively intact, elderly controls completed 18F-ASEM PET. "

01/01/2021 - "After damage of endothelial cells and primary plaque formation, 18F-ASEM imaging of atherosclerotic plaques linked to α7nAChR had been conducted. "
01/01/2021 - "Thus, 18F-ASEM could be a complementary diagnostic approach to atherosclerotic plaques. "
01/01/2021 - "In vivo micro-PET/CT imaging of ApoE-/- mice and the control group was performed 1 h after injection of 18F-ASEM (100-150 μCi); PET/CT imaging for rabbits with atherosclerotic plaques and control ones was also performed. "
01/01/2021 - "18F-ASEM Imaging for Evaluating Atherosclerotic Plaques Linked to α7-Nicotinic Acetylcholine Receptor."
01/01/2021 - "Compared with 18F-FDG, 18F-ASEM had more significant effect on the early monitoring of inflammation in carotid atherosclerotic plaques of ApoE-/- mice and model rabbits. "

01/01/2021 - "18F-ASEM had relatively more palpable effect on the imaging of abdominal aorta with atherosclerosis in rabbits. "
01/01/2021 - "In vivo vessel binding of 18F-ASEM and α7nAChR expression in the model group with atherosclerosis plaques was significantly higher than that in the control group. "