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3'-methoxy-E-diethylstilbestrol

structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Stilbestrols: 1
        Diethylstilbestrol: 1652
        3'-methoxy-E-diethylstilbestrol: 1

Experts

1.	Jin, Weiwei: 1 article (04/2012)
2.	Liu, Qian: 1 article (04/2012)
3.	Lu, Min: 1 article (04/2012)
4.	Zhang, Qian: 1 article (04/2012)
5.	Zhou, Jieyun: 1 article (04/2012)
6.	Zhu, Yan: 1 article (04/2012)

Related Diseases

1.

Neoplasms (Cancer)

04/01/2012 - "3'-Methoxy-E-diethylstilbestrol (2), with the structural and original similarities to 2-methoxyestradiol (2-ME2, 1), was synthesized and screened against HUVEC and a series of human cancer cell lines including RL95-2, SKOV-3, MCF-7 and T-47D in vitro. "
04/01/2012 - "Synthesis of 3'-methoxy-E-diethylstilbestrol and its analogs as tumor angiogenesis inhibitors."
04/01/2012 - "The fact that 3'-methoxy-E-diethylstilbestrol and its analogues (8 and 11) showed potential antiangiogenesis and anti-tumor activities at a close level, whereas its ester derivative (10) did not display any cytotoxic activities on all the screening cell lines indicated that the core scaffold of 3'-methoxy-3,4-diphenylhexane and the exposed hydroxyl-groups in the structures are essential pharmacophores for their anti-tumor activities."

Related Drugs and Biologics

1.	Angiogenesis Inhibitors
2.	Hydroxyl Radical
3.	Esters
4.	2-Methoxyestradiol