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selgantolimod

toll-like receptor 8 agonist

Also Known As:

(R)-2-((2-amino-7-fluoropyrido(3,2-d)pyrimidin-4-yl)amino)-2-methylhexan-1-ol; GS-9688

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Fatty Alcohols: 172
    - Hexanols: 17
      - selgantolimod: 5
Lipids: 114793
- Fatty Alcohols: 172
  - Hexanols: 17
    - selgantolimod: 5
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - selgantolimod: 5

Experts

1.	Daffis, Stephane: 4 articles (01/2021 - 01/2020)
2.	Fletcher, Simon P: 4 articles (01/2021 - 01/2020)
3.	Gaggar, Anuj: 2 articles (10/2021 - 01/2020)
4.	Gane, Edward J: 2 articles (10/2021 - 01/2020)
5.	Tan, Susanna K: 2 articles (10/2021 - 01/2020)
6.	Chamberlain, Jason: 2 articles (01/2021 - 01/2020)
7.	Chu, Ruth: 2 articles (01/2021 - 01/2021)
8.	Delaney, William E: 2 articles (01/2021 - 01/2020)
9.	Mish, Michael: 2 articles (01/2021 - 01/2020)
10.	Pattabiraman, Divya: 2 articles (01/2021 - 01/2021)

Related Diseases

1.

Chronic Hepatitis B

10/01/2021 - "Safety, Pharmacokinetics, and Pharmacodynamics of the Oral TLR8 Agonist Selgantolimod in Chronic Hepatitis B."
01/01/2021 - "Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B."
01/01/2020 - "Selgantolimod is a novel oral, selective Toll-like receptor 8 (TLR8) agonist in development for the treatment of chronic hepatitis B (CHB). "
01/01/2021 - "GS-9688 (selgantolimod) is a toll-like receptor 8 agonist in clinical development for the treatment of chronic hepatitis B (CHB). "
01/01/2021 - "Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators."

Related Drugs and Biologics

1.	selgantolimod
2.	Toll-Like Receptor 8
3.	Antiviral Agents (Antivirals)