HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

CCTA-1523

an ABCG2 protein inhibitor; structure in first source

Also Known As:

2,2-dichloro-N-(3',4'-dimethoxy-(1,1'-biphenyl)-3-yl)acetamide

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Anilides: 22
      - Acetanilides: 7
        CCTA-1523: 1
- Amides: 2428
  - Anilides: 22
    - Acetanilides: 7
      - CCTA-1523: 1

Experts

1.	Anreddy, Nagaraju: 1 article (07/2017)
2.	Chen, Zhe-Sheng: 1 article (07/2017)
3.	Cheng, Changmei: 1 article (07/2017)
4.	Gadhia, Sanket: 1 article (07/2017)
5.	Kathawala, Rishil: 1 article (07/2017)
6.	Li, Tian-Wen: 1 article (07/2017)
7.	Patel, Atish: 1 article (07/2017)
8.	Sodani, Kamlesh: 1 article (07/2017)
9.	Wang, De-Shen: 1 article (07/2017)
10.	Yang, Dong-Hua: 1 article (07/2017)

Related Diseases

1.

Neoplasms (Cancer)

07/01/2017 - "Taken together, our findings indicate that CCTA-1523 is a potent, selective and reversible modulator of ABCG2 that may offer therapeutic promise for multidrug- resistant malignancies."
07/01/2017 - "CCTA-1523 (5μM) sensitized the ABCG2 overexpressing cancer cells and ABCG2 transfected cells to the substrate chemotherapeutic drugs. "
07/01/2017 - "An analysis of structural congeners among a group of compounds led to the discovery of CCTA-1523 that could selectively reverse ABCG2-mediated MDR in cancer cells in vitro and in vivo. "
07/01/2017 - "Importantly, co-administration of CCTA-1523 restored the in vivo antitumor activity of doxorubicin in ABCG2 overexpressing tumor xenografts. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)