Renato Leonardo de Freitas Selected Research

Neuralgia (Stump Neuralgia)

12/2023	Cortical Neurostimulation and N-Methyl-D-Aspartate Glutamatergic Receptor Activation in the Dysgranular Layer of the Posterior Insular Cortex Modulate Chronic Neuropathic Pain.
7/2023	Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid.
10/2021	The primary motor cortex electrical and chemical stimulation attenuates the chronic neuropathic pain by activation of the periaqueductal grey matter: The role of NMDA receptors.
1/2021	An Adapted Chronic Constriction Injury of the Sciatic Nerve Produces Sensory, Affective, and Cognitive Impairments: A Peripheral Mononeuropathy Model for the Study of Comorbid Neuropsychiatric Disorders Associated with Neuropathic Pain in Rats.
12/2020	CB1-cannabinoid-, TRPV1-vanilloid- and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain symptoms.
1/2020	Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice.
9/2019	N-methyl-D-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain.

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Renato Leonardo de Freitas Research Topics

Disease

7	Hyperalgesia 12/2023 - 09/2019
7	Neuralgia (Stump Neuralgia) 12/2023 - 09/2019
7	Seizures (Absence Seizure) 12/2016 - 10/2004
3	Pain (Aches) 01/2014 - 04/2012
2	Panic Disorder (Panic Attack) 01/2019 - 06/2014
1	Schizophrenia (Dementia Praecox) 12/2023
1	Epilepsy (Aura) 10/2004

Drug/Important Bio-Agent (IBA)

6	N-Methylaspartate (NMDA)IBA 12/2023 - 06/2014
3	AcetoneIBA 12/2023 - 07/2023
3	gamma-Aminobutyric Acid (GABA)IBA 12/2016 - 10/2004
3	Pentylenetetrazole (Metrazol)IBA 12/2016 - 10/2004
2	salicylhydroxamic acid (SHAM)IBA 12/2023 - 12/2023
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2021 - 09/2019
2	LY 235959IBA 10/2021 - 09/2019
2	Opioid Receptors (Opioid Receptor)IBA 01/2019 - 12/2016
2	Opioid Peptides (Opioid Peptide)IBA 01/2019 - 04/2012
2	naloxonazineIBA 12/2016 - 02/2012
2	Aminobutyrates (Aminobutyric Acid)IBA 11/2016 - 06/2014
2	cobaltous chloride (cobalt(II)chloride)IBA 01/2014 - 05/2013
2	Serotonin (5 Hydroxytryptamine)IBA 01/2014 - 04/2013
2	Cholinergic Agents (Cholinergics)IBA 05/2013 - 10/2004
2	Cholinergic ReceptorsIBA 05/2013 - 10/2004
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2013 - 10/2011
1	Haloperidol (Haldol)FDA LinkGeneric 12/2023
1	Antipsychotic Agents (Antipsychotics)IBA 12/2023
1	N1,N8- bis(2,5- dihydroxybenzoyl)spermidineIBA 07/2023
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 12/2020
1	TRPV1 receptorIBA 12/2020
1	Glutamate Receptors (Glutamate Receptor)IBA 09/2019
1	Naloxone (Narcan)FDA LinkGeneric 01/2019
1	Narcotic Antagonists (Opioid Antagonists)IBA 12/2016
1	Naltrexone (ReVia)FDA LinkGeneric 12/2016
1	Opioid Analgesics (Opioids)IBA 11/2016
1	IonophoresIBA 11/2016
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 06/2014
1	Kainic Acid Receptors (Kainate Receptor)IBA 06/2014
1	Atropine FDA LinkGeneric 05/2013
1	MecamylamineIBA 05/2013
1	Dimenhydrinate (DMH)FDA LinkGeneric 04/2013
1	Sucrose (Saccharose)IBA 04/2012

Therapy/Procedure

2	Therapeutics 12/2023 - 10/2021
2	Ligation 01/2021 - 01/2020
2	Analgesia 05/2013 - 10/2004